Medical Underground

Medical Underground

TMG:

THE UNKNOWN FAT DESTROYER

Dr. Ralph La Guardia's avatar
Dr. Ralph La Guardia
Jul 02, 2026
∙ Paid

TMG (trimethyl glycine) is a naturally occurring compound composed of glycine with three methyl groups attached. It is produced by the body and found in foods like beets, spinach, quinoa, and wheat bran, but supplementation can help achieve optimal levels for specific health goals. In this week’s Medical Underground, we are going to take our usual deep dive and see what all the hype is about.

TMG, also known as betaine, is a supplement that supports methylation, cardiovascular health, liver function, and athletic performance. It has become a favorite of many people because of these many benefits. But is it all true?

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Betaine has many positive side effects such as:

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